
Distinct Circuit Mechanisms in Epilepsies San Diego | November 13-14, 2025

Preliminary Program
Day One Thursday, November 13
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8:00-9:00am Breakfast
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9:00-10:40am Session 1: Identifying circuit dysfunction in epilepsy
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Discussion Leader: John Huguenard, Stanford
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Speakers:
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Doug Coulter, Penn
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TBD​
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Joanna Mattis, U Michigan
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Subcortical Neuromodulatory Networks In a Dravet Syndrome Model​
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Jeanne Paz, UCSF
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A Dual Inhibitory Network in the Thalamic Reticular Nucleus Delineated by Pallidal and Intra-Reticular Inhibition​
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10:40-11:00am Coffee Break
11:00-12:40pm Session 2: Abnormal circuit development in epilepsy
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Discussion Leader: Dr. Juliet Knowles, Stanford
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Speakers:
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Gabrielle Devienne, Stanford
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Prefrontal Cortex Maturation in Typical and Neurodevelopmental Conditions​
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Xiaoming Jin, Indiana U​
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Homeostatic Plasticity in the Development and Treatment of Posttraumatic Epilepsy and Neuropathic Pain​
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Mark Beenhakker, U of Virginia
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Resolving global neuronal synchrony in childhood absence epilepsy​
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12:40-2:00pm Lunch
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2:00-5:00pm Rigor in Science & Poster session
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Speakers:
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Anita Bandrowski, Founder and CEO at SciCrunch
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Should electrophysiologists care about rigor and transparency?
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Trainee Presentations
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6:00pm Dinner
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Day Two Friday, November 14
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8:00-9:00am Breakfast
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9:00-10:40am Session 3: Ion channel dysfunction in epilepsy
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Discussion Leader: Mark Beenhakker
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Speakers:
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Ethan Goldberg, Penn
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Ionic mechanisms underlying temperature-sensitive seizures​
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Chris Makinson, Columbia
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TBD​
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Mike Gutnick, Hebrew U of Jerusalem
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Half a century of spikes, circuits and pathology​
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10:40-11:00am Coffee Break
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11:00-12:40pm Session 4: Glial signaling and epileptogenesis
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Discussion Leader: Ethan Goldberg, Penn
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Speakers:
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Juliet Knowles, Stanford
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Maladaptive myelination promotes generalized epilepsy progression​
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Annalisa Scimemi, SUNY Albany
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Small Things Make Big Differences: Why Regulating Glutamate Escape Transforms Hippocampal Activity​
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Chris Dulla, Tufts
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​Why does loss of GABA transport cause epilepsy?​​
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12:40-2:00pm Lunch
2:00-3:40pm Session 5: Mechanisms of co-morbidities in epilepsy
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Discussion Leader: Brielle Ferguson
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Speakers:
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Vikaas Sohal, UCSF
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Inhibitory circuit dysfunction and aberrant synchronization in neuropsychiatric disease​
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Laura Ewell, UC Irvine
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Interictal Spikes - Mechanisms and Impacts On Memory​
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Trent Anderson, U Arizona
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Head-Banging Neurons: Circuits Driving Post-Traumatic Headache​
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3:40-4:00pm Coffee Break
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4:00-5:40pm Session 6: New models of circuit dysfunction
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Discussion Leader: Kevin Staley, Harvard
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Speakers:
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Jacob Hull, Stanford
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​Modeling Complexity: Interpretable Machine Learning Identifies a Multiregional Absence Seizure Mechanism
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Omer Revah, Hebrew U of Jerusalem
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From Organoids to Circuits: Novel Cortical Models for Understanding Neurodevelopmental Disorders​
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Qian-Quan Sun, U Wyoming
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​Elucidating Epileptogenic Mechanisms in a Mouse Model of Focal Cortical Dysplasia
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